Các thử nghiệm lâm sàng đã xuất bản vào ngày
Viện nghiên cứu nhân sâm Hàn Quốc
Tập đoàn Nhân sâm Hàn Quốc đang thúc đẩy đổi mới với Viện Nghiên cứu Nhân sâm Hàn Quốc đứng đầu. Viện Nghiên cứu Nhân sâm Hàn Quốc có 130 nhà nghiên cứu hàng đầu liên quan đến y học và khoa học, cả trong nước và toàn cầu. Chúng tôi nghiên cứu nhiều chủ đề khác nhau và chúng tôi dẫn đầu thế giới về nghiên cứu nhân sâm đỏ và các sản phẩm tự nhiên trong các lĩnh vực từ công nghệ trồng nhân sâm đến phát triển thành phần mới, nghiên cứu phân tích hiệu quả / an toàn, phát triển sản phẩm, v.v.
Hair Regrowth
How Korean Red Ginseng Treats Alopecia Areata
Oh GN et al. “Efficacy of Korean Red Ginseng in the Treatment of Alopecia Areata” J Ginseng Res. 2012;36(4):391-395.
The effect of Korean red ginseng (KRG) on alopecia areata (AA):
AA is an autoimmune disease that can affect any hair-bearing area. Though many therapeutic modalities have been used to treat AA, none of these agents is definitely curative or preventive alone. In Korea, KRG is well known to effective for prevention of hair loss and growth of hair. However, there are still no reports of the efficacy of KRG in AA using medical engineering techniques. Thus, the authors studied hair growth efficacy and safety of KRG in AA.
Results:
This study results suggest that treatment with KRG can result in improved hair regrowth in AA patients.
Conclusion:
This study proved the efficacy of KRG in the treatment of AA, recommending KRG as a useful complementary food for management of AA.
The effect of Korean red ginseng (KRG) on alopecia areata (AA):
AA is an autoimmune disease that can affect any hair-bearing area. Though many therapeutic modalities have been used to treat AA, none of these agents is definitely curative or preventive alone. In Korea, KRG is well known to effective for prevention of hair loss and growth of hair. However, there are still no reports of the efficacy of KRG in AA using medical engineering techniques. Thus, the authors studied hair growth efficacy and safety of KRG in AA.
Results:
This study results suggest that treatment with KRG can result in improved hair regrowth in AA patients.
Conclusion:
This study proved the efficacy of KRG in the treatment of AA, recommending KRG as a useful complementary food for management of AA.
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Obesity
How Korean Red Ginseng Has An Impact On Obesity Indices By Gene
Kwon DH et al. “Efficacy of Korean Red Ginseng by Single Nucleotide Polymorphism in Obese Women: Randomized, Double-blind, Placebo-controlled Trial” J
Ginseng Res. 2012;36(2):176-189.
The effect of Korean red ginseng (KRG) on obesity:
Obesity is caused by the imbalance of energy metabolism. KRG or ginseng has been proven to be very effective for improving obesity and abnormal metabolism in animal studies and clinical studies. These effects of KRG and ginseng on the treatment of obesity can be thought to be greater in the obesity caused by reduced energy metabolism. This study examined the effects of KRG on obese women and aimed to confirm that the effects of KRG on obesity differ dependently on a gene.
Results:
KRG is more effective for improving the secondary issues of the quality of life derived from obesity rather than having direct effects on the obesity-related anthropometric assessment and blood test indices.
Conclusion:
This study tried to examine the differences of the effects of KRG on the obesity indices by gene mutation.
KRG is more effective for improving the secondary issues of the quality of life derived from obesity rather than having direct effects on the obesity-related anthropometric assessment and blood test indices.
The effect of Korean red ginseng (KRG) on obesity:
Obesity is caused by the imbalance of energy metabolism. KRG or ginseng has been proven to be very effective for improving obesity and abnormal metabolism in animal studies and clinical studies. These effects of KRG and ginseng on the treatment of obesity can be thought to be greater in the obesity caused by reduced energy metabolism. This study examined the effects of KRG on obese women and aimed to confirm that the effects of KRG on obesity differ dependently on a gene.
Results:
KRG is more effective for improving the secondary issues of the quality of life derived from obesity rather than having direct effects on the obesity-related anthropometric assessment and blood test indices.
Conclusion:
This study tried to examine the differences of the effects of KRG on the obesity indices by gene mutation.
KRG is more effective for improving the secondary issues of the quality of life derived from obesity rather than having direct effects on the obesity-related anthropometric assessment and blood test indices.
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Sexual Function
How Korean Red Ginseng Could Be A Useful Agent For Treating Male Infertility
Park HJ et al. “Effects of Korean Red Ginseng on Semen Parameters in Male Infertility Patients: A Randomized Placebo-Controlled, Double-Blind Clinical
Study” Chin J Integr Med. 2016;22(7):490-495.
The effect of Korean red ginseng (KRG) on male infertility:
Many empirical treatments have been used to improve the quality and concentration of sperm, although good results have not been achieved. Several studies have also reported that ginseng improves spermatogenesis in animals. These effects were probably caused by anti-oxidant and anti-aging actions, as well as modulation of the hypothalamuspituitary-testis axis. This study was to investigate the effects of KRG on semen parameters in male infertility patients.
Results:
KRG-treated groups with or without varicocelectomy showed significantly improved semen parameters in terms of sperm concentration, viability, motility, and morphology.
Conclusion
As the treatment with KRG for 12 weeks enhanced spermatogenesis, KRG may be a useful agent for the treatment of male infertility.
The effect of Korean red ginseng (KRG) on male infertility:
Many empirical treatments have been used to improve the quality and concentration of sperm, although good results have not been achieved. Several studies have also reported that ginseng improves spermatogenesis in animals. These effects were probably caused by anti-oxidant and anti-aging actions, as well as modulation of the hypothalamuspituitary-testis axis. This study was to investigate the effects of KRG on semen parameters in male infertility patients.
Results:
KRG-treated groups with or without varicocelectomy showed significantly improved semen parameters in terms of sperm concentration, viability, motility, and morphology.
Conclusion
As the treatment with KRG for 12 weeks enhanced spermatogenesis, KRG may be a useful agent for the treatment of male infertility.
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Sleep Quality
How Korean Red Ginseng Has Beneficial Effects On Sleep Quality
Han HJ et al. “Effects of red ginseng extract on sleep behaviors in human volunteers” J Ethnopharmacol. 2013;149:597-599
The effect of Korean red ginseng (KRG) on sleep:
The ginseng root has been traditionally used as a sedative in oriental countries. However, the condition “ginseng abuse syndrome”, was coined as a result of a study of people who had been using a variety of ginseng preparations. However, we reported that administration of KRG increased rapid eye movement and non rapid eye sleep via GABAergic systems in animals. Therefore, this study was performed to investigate KRG affects sleeping behaviors in human volunteers.
Results:
Administration of Korean red ginseng significantly reduced the total wake time and increased the sleep efficiency, while reducing N1 and improving REM sleep.
Conclusion:
From these results, it is presumed that KRG intake does not interfere with sleep, but rather improves the quality of sleep, thus having beneficial effects on sleep disturbed subjects.
The effect of Korean red ginseng (KRG) on sleep:
The ginseng root has been traditionally used as a sedative in oriental countries. However, the condition “ginseng abuse syndrome”, was coined as a result of a study of people who had been using a variety of ginseng preparations. However, we reported that administration of KRG increased rapid eye movement and non rapid eye sleep via GABAergic systems in animals. Therefore, this study was performed to investigate KRG affects sleeping behaviors in human volunteers.
Results:
Administration of Korean red ginseng significantly reduced the total wake time and increased the sleep efficiency, while reducing N1 and improving REM sleep.
Conclusion:
From these results, it is presumed that KRG intake does not interfere with sleep, but rather improves the quality of sleep, thus having beneficial effects on sleep disturbed subjects.
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Depression
How Korean Red Ginseng Could Be Efficacious For Major Depression
Jeong HG et al. “Effect of Korean Red Ginseng as an adjuvant treatment for women with residual symptoms of major depression” Asia Pac Psychiatry.
2015;7(3):330-336.
The effect of Korean red ginseng (KRG) on depression:
Depression is considered as a serious illness, but can be cured as various pharmacological agents become more readily available. Ginseng has shown potential antidepressant effects in some animal studies and in patients with stress-related somatic symptoms. Therefore, we investigated the effectiveness and tolerability of KRG adjuvant treatment in patients with residual symptoms of major depression.
Results:
The subjects reported significant decrease in depressive symptoms on DRSS, MADRS and CGI-S and in somatic symptoms on DSSS over the eight-week study period of taking Korean red ginseng.
Conclusion:
These study results suggest that Korean red ginseng is effective and safe in patients experiencing residual symptoms of depression, indicating the feasibility of Korean red ginseng as an alternative treatment option for patients with depression and other related disorders.
The effect of Korean red ginseng (KRG) on depression:
Depression is considered as a serious illness, but can be cured as various pharmacological agents become more readily available. Ginseng has shown potential antidepressant effects in some animal studies and in patients with stress-related somatic symptoms. Therefore, we investigated the effectiveness and tolerability of KRG adjuvant treatment in patients with residual symptoms of major depression.
Results:
The subjects reported significant decrease in depressive symptoms on DRSS, MADRS and CGI-S and in somatic symptoms on DSSS over the eight-week study period of taking Korean red ginseng.
Conclusion:
These study results suggest that Korean red ginseng is effective and safe in patients experiencing residual symptoms of depression, indicating the feasibility of Korean red ginseng as an alternative treatment option for patients with depression and other related disorders.
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Vascular Disorder
How Korean Red Ginseng Could Have Beneficial Effects On Coronary Artery Disease
Chung IM et al. “Korean red ginseng improves vascular stiffness in patients with coronary artery disease” J Ginseng Res. 2010;34(3):212-218.
The effect of Korean red ginseng (KRG) on coronary artery disease (CAD):
Endothelial dysfunction is regarded as not only the earliest manifestation of atherosclerosis but also as a prognostic factor for adverse cardiovascular events. KRG has diverse effects on the vasculature, improving endothelial function. The aim of this study was to determine whether KRG has an effect on arterial stiffness and cardiovascular risk factors in patients with CAD.
Results:
Korean red ginseng treatment for 10 weeks reduced the systolic blood pressure and the vascular stiffness in the central aorta and peripheral muscular arteries, probably via the inhibition of ROCK activity in patients with coronary artery disease.
Conclusion:
The Korean red ginseng-induced effects in this study suggest the need of further study for understanding the pharmacological effects of Korean red ginseng on the progression of atherosclerotic plaque formation and the prevention of acute coronary syndrome in patients with coronary artery disease.
The effect of Korean red ginseng (KRG) on coronary artery disease (CAD):
Endothelial dysfunction is regarded as not only the earliest manifestation of atherosclerosis but also as a prognostic factor for adverse cardiovascular events. KRG has diverse effects on the vasculature, improving endothelial function. The aim of this study was to determine whether KRG has an effect on arterial stiffness and cardiovascular risk factors in patients with CAD.
Results:
Korean red ginseng treatment for 10 weeks reduced the systolic blood pressure and the vascular stiffness in the central aorta and peripheral muscular arteries, probably via the inhibition of ROCK activity in patients with coronary artery disease.
Conclusion:
The Korean red ginseng-induced effects in this study suggest the need of further study for understanding the pharmacological effects of Korean red ginseng on the progression of atherosclerotic plaque formation and the prevention of acute coronary syndrome in patients with coronary artery disease.
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Skin Disorder
How Korean Red Ginseng Could Have Beneficial Effects On Atopic Dermatitis
Kim H et al. “The beneficial effect of Korean red ginseng extract on atopic dermatitis patients” Ann Dermatol. 2018;30(3):304-308.
The effect of Korean red ginseng (KRG) on atopic dermatitis (AD):
AD is a chronic or chronically relapsing, eczematous, severely pruritic inflammatory skin disorder. KRG has been shown previously to exhibit diverse biological effects including anti-inflammatory and antipruritic effects in a murine model. We aimed to investigate the beneficial effects of KRG on AD patients, to determine whether there was improvement in disease severity, skin barrier function, pruritus and sleep disturbance relief.
Results:
Korean red ginseng not only improves the general well-being of the patients, but also restores the skin barrier function through reduction of TEWL.
Conclusion:
This study suggest that KRG can be safely used as a supplement remedy leading to clinical improvement of AD, can improve overall quality of life, and has potential for further development.
The effect of Korean red ginseng (KRG) on atopic dermatitis (AD):
AD is a chronic or chronically relapsing, eczematous, severely pruritic inflammatory skin disorder. KRG has been shown previously to exhibit diverse biological effects including anti-inflammatory and antipruritic effects in a murine model. We aimed to investigate the beneficial effects of KRG on AD patients, to determine whether there was improvement in disease severity, skin barrier function, pruritus and sleep disturbance relief.
Results:
Korean red ginseng not only improves the general well-being of the patients, but also restores the skin barrier function through reduction of TEWL.
Conclusion:
This study suggest that KRG can be safely used as a supplement remedy leading to clinical improvement of AD, can improve overall quality of life, and has potential for further development.
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Cognitive Function
How Korean Red Ginseng Has A Beneficial Effect On Concentration
Yeo, HB et al. “Effects of Korean red ginseng on cognitive and motor function: a double-blind, randomized, placebo-controlled trial” J Ginseng Res. 2012;36(2):190.
The effect of Korean red ginseng (KRG) on cognitive function:
There is some evidence from animal studies that ginseng has a beneficial effect on cognitive performance. KRG was shown in one study to significantly reduce the P300 latency, suggesting that it can directly modulate cerebro-electrical activity. The current study used the P300 event-related potential (ERP) and the neurocognitive function test to investigate the effect of KRG on cognitive performance.
Results:
The decreased P300 latency may indicate an improvement in cognitive function, especially in association with attention allocation, immediate memory and behavior reaction time.
Conclusion:
The KRG group showed a decreased P300 latency in the central area, suggesting that the decreased latency in ERP after KRG supplementation is associated with improved cognitive function.
The effect of Korean red ginseng (KRG) on cognitive function:
There is some evidence from animal studies that ginseng has a beneficial effect on cognitive performance. KRG was shown in one study to significantly reduce the P300 latency, suggesting that it can directly modulate cerebro-electrical activity. The current study used the P300 event-related potential (ERP) and the neurocognitive function test to investigate the effect of KRG on cognitive performance.
Results:
The decreased P300 latency may indicate an improvement in cognitive function, especially in association with attention allocation, immediate memory and behavior reaction time.
Conclusion:
The KRG group showed a decreased P300 latency in the central area, suggesting that the decreased latency in ERP after KRG supplementation is associated with improved cognitive function.
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Immunity
How Korean Red Ginseng Boosts The Immune System
Hyun, SH et al. “Immuno-enhancement effects of Korean Red Ginseng in healthy adults: a randomized, double-blind, placebo-controlled trial” J Ginseng Res.
2021;45(1):191-198.
The immunoactivity of Korean red ginseng (KRG) for healthy controls:
Natural foods come up in the discourse around enhancing bodily functions, one of which is ginseng. Most clinical studies of immune responses activated by KRG have been conducted exclusively in patients. However, there is still a lack of clinical research on immune boosting benefits of KRG for healthy persons. This study aims to confirm how KRG boosts the immune system of healthy subjects
Results:
The significantly increased T cell, B cell and WBC levels confirmed that KRG increases immunity not only for cancer patients but also for healthy subjects with reduced immunity.
Conclusion:
Through 8-week intake test and subsequent analysis, KRG was proven its safety and immune boosting activity. KRG increases the number of immune cells to help improve immunity when consumed by healthy adults with slightly downregulated immunity as an excellent immunopotentiator.
The immunoactivity of Korean red ginseng (KRG) for healthy controls:
Natural foods come up in the discourse around enhancing bodily functions, one of which is ginseng. Most clinical studies of immune responses activated by KRG have been conducted exclusively in patients. However, there is still a lack of clinical research on immune boosting benefits of KRG for healthy persons. This study aims to confirm how KRG boosts the immune system of healthy subjects
Results:
The significantly increased T cell, B cell and WBC levels confirmed that KRG increases immunity not only for cancer patients but also for healthy subjects with reduced immunity.
Conclusion:
Through 8-week intake test and subsequent analysis, KRG was proven its safety and immune boosting activity. KRG increases the number of immune cells to help improve immunity when consumed by healthy adults with slightly downregulated immunity as an excellent immunopotentiator.
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Menopausal Symptoms
How Korean Red Ginseng Could Act As A Supplement For Relieving Menopausal Symptoms
Kim, SY et al. “Effects of red ginseng supplementation on menopausal symptoms and cardiovascular risk factors in postmenopausal women: a double-blind
randomized controlled trial” Menopause. 2012;19(4):461-466.
The effect of red ginseng (RG) on menopausal symptoms:
Red Ginseng has been widely used to treat diseases such as cancer and cardiovascular disease (CVD) in East Asian countries. Previous studies have shown that Red Ginseng is effective against the psychological and emotional symptoms that are common in postmenopausal women. The aim of this study was to evaluate the effects of Red Ginseng on menopausal symptoms and cardiovascular risk factors in postmenopausal women.
Results:
The significantly increased T cell, B cell and WBC levels confirmed that KRG increases immunity not only for cancer patients but also for healthy subjects with reduced immunity.
Conclusion:
The Red Ginseng could be an attractive herbal dietary supplement for relieving menopausal symptoms and conferring favorable effects on markers of cardiovascular disease in postmenopausal women.
The effect of red ginseng (RG) on menopausal symptoms:
Red Ginseng has been widely used to treat diseases such as cancer and cardiovascular disease (CVD) in East Asian countries. Previous studies have shown that Red Ginseng is effective against the psychological and emotional symptoms that are common in postmenopausal women. The aim of this study was to evaluate the effects of Red Ginseng on menopausal symptoms and cardiovascular risk factors in postmenopausal women.
Results:
The significantly increased T cell, B cell and WBC levels confirmed that KRG increases immunity not only for cancer patients but also for healthy subjects with reduced immunity.
Conclusion:
The Red Ginseng could be an attractive herbal dietary supplement for relieving menopausal symptoms and conferring favorable effects on markers of cardiovascular disease in postmenopausal women.
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Stamina
How Korean Red Ginseng Shows Therapeutic Potential For People With Chronic Fatigue
Sung, WS et al. “Efficacy of Korean red ginseng (Panax ginseng) for middle-aged and moderate level of chronic fatigue patients: A randomized, double-blind,
placebo-controlled trial” Complement Ther Med. 2020;48, 102246.
The effect of Korean red ginseng (KRG) on chronic fatigue (CF):
CF is unexplained fatigue lasting more than 6 months. Several studies demonstrated the role of oxidative stress in CF and suggested the administration of antioxidants as a potential treatment. KRG is known to have higher anti-fatigue substance than white ginseng. The purpose of this study was to investigate the effect of KRG on CF by various measurements and objective indicators.
Results:
KRG provided the objective evidence of fatigue-related measurement and the therapeutic potential for middle-aged individuals with moderate fatigue.
Conclusion:
KRG demonstrated its safety and efficacy for patients with chronic fatigue, suggesting its potential for treating a subset of patients with chronic fatigue (moderate or idiopathic chronic fatigue.
The effect of Korean red ginseng (KRG) on chronic fatigue (CF):
CF is unexplained fatigue lasting more than 6 months. Several studies demonstrated the role of oxidative stress in CF and suggested the administration of antioxidants as a potential treatment. KRG is known to have higher anti-fatigue substance than white ginseng. The purpose of this study was to investigate the effect of KRG on CF by various measurements and objective indicators.
Results:
KRG provided the objective evidence of fatigue-related measurement and the therapeutic potential for middle-aged individuals with moderate fatigue.
Conclusion:
KRG demonstrated its safety and efficacy for patients with chronic fatigue, suggesting its potential for treating a subset of patients with chronic fatigue (moderate or idiopathic chronic fatigue.
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Antioxidants
How Korean Red Ginseng Upregulates Antioxidant Enzyme Activity
Kim JY et al. “Beneficial effects of Korean red ginseng on lymphocyte DNA damage, antioxidant enzyme activity, and LDL oxidation in healthy participants: a
randomized, double-blind, placebo-controlled trial” Nutr J. 2012;11(1), 1-9.
The beneficial effect of Korean red ginseng (KRG) on antioxidant enzyme activity:
Oxidative stress describes a set of intracellular or extracellular conditions that lead to the chemical or metabolic generation of reactive oxygen/nitrogen species. The reported health benefits of Korean red ginseng (KRG) include antioxidant, antitumor, antimutagenic, and immunomodulatory activities; however, the effects on oxidative stress have not yet been evaluated. Therefore, we assessed the effect of KRG on antioxidant enzymes and oxidative stress markers in humans.
Results:
KRG supplementation improved biomarkers of oxidative stress, as evidenced by decrease plasma oxidized LDL, attenuated lymphocyte DNA damage and increase plasma antioxidant enzyme activity in healthy participants.
Conclusion:
KRG supplementation may attenuate lymphocyte DNA damage and LDL oxidation by upregulating antioxidant enzyme activity.
The beneficial effect of Korean red ginseng (KRG) on antioxidant enzyme activity:
Oxidative stress describes a set of intracellular or extracellular conditions that lead to the chemical or metabolic generation of reactive oxygen/nitrogen species. The reported health benefits of Korean red ginseng (KRG) include antioxidant, antitumor, antimutagenic, and immunomodulatory activities; however, the effects on oxidative stress have not yet been evaluated. Therefore, we assessed the effect of KRG on antioxidant enzymes and oxidative stress markers in humans.
Results:
KRG supplementation improved biomarkers of oxidative stress, as evidenced by decrease plasma oxidized LDL, attenuated lymphocyte DNA damage and increase plasma antioxidant enzyme activity in healthy participants.
Conclusion:
KRG supplementation may attenuate lymphocyte DNA damage and LDL oxidation by upregulating antioxidant enzyme activity.
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Blood Circulation
How Korean Red Ginseng Exerts The Restorative Effect On Microvascular Integrity In Patients With Acute Myocardial Infarction
Ahn CM et al. “Red Ginseng Extract Improves Coronary Flow Reserve and Increases Absolute Numbers of Various Circulating Angiogenic Cells in Patients with
First ST-Segment Elevation Acute Myocardial Infarction” Psychother Res. 2011;25:239-245.
The effect of Korean red ginseng (KRG) on coronary flow reserve:
Baseline coronary flow reserve (CFR) has been used as a predictor of improvement in left ventricular function after AMI (acute myocardial infarction) however, baseline and 8-month follow-up CFR values have never been compared in ST-elevation AMI patients after KRG extract administration. Therefore, in this study, the effects of red ginseng extract on circulating angiogenic cell mobilization and improvement of microvascular integrity were compared in ST-segment elevation AMI patients during an 8-month follow-up period.
Results:
Improvement of coronary flow reserve and increase of circulating angiogenic cells KRG improved CFR in first ST-elevation and increased circulating angiogenic cell mobilization and decreased inflammation in AMI patients during the 8-month follow-up.
Conclusion:
3g /day of KRG for 8 months is an effective and safe treatment for first ST-elevation AMI patients, possibly by restoration of microvascular function.
The effect of Korean red ginseng (KRG) on coronary flow reserve:
Baseline coronary flow reserve (CFR) has been used as a predictor of improvement in left ventricular function after AMI (acute myocardial infarction) however, baseline and 8-month follow-up CFR values have never been compared in ST-elevation AMI patients after KRG extract administration. Therefore, in this study, the effects of red ginseng extract on circulating angiogenic cell mobilization and improvement of microvascular integrity were compared in ST-segment elevation AMI patients during an 8-month follow-up period.
Results:
Improvement of coronary flow reserve and increase of circulating angiogenic cells KRG improved CFR in first ST-elevation and increased circulating angiogenic cell mobilization and decreased inflammation in AMI patients during the 8-month follow-up.
Conclusion:
3g /day of KRG for 8 months is an effective and safe treatment for first ST-elevation AMI patients, possibly by restoration of microvascular function.
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Liver Disease
How Korean Red Ginseng Could Act As Liver Cancer Preventative
Abdel-Wahhab MA et al. “Therapeutic effects of Korean red ginseng extract in Egyptian patients with chronic liver disease” J Ginseng Res. 2011;35(1):69-79.
The effect of Korean red ginseng (KRG) on hepatocellular carcinoma (HCC):
HCC is the fifth most common malignancy in the world and complicates liver cirrhosis related to hepatitis C virus in many cases. Several studies have found that the antitumor activity of a novel ginseng saponin metabolite (IH-901) is attributable to the induction of apoptosis. The aim of the current study was to evaluate the therapeutic effects of KRG extract in Egyptian patients with chronic liver diseases.
Results:
This study results showed that the medical therapy alone failed to normalize the liver enzymes or decrease the virus concentration. Korean red ginseng administration induced a significant improvement in liver function tests, decreased the tumor marker levels, and decreased the viral titers in HCV patients.
Conclusion:
The results of the current study indicate that Korean red ginseng could act as liver cancer preventative as well as an antiviral agent against HCV.
The effect of Korean red ginseng (KRG) on hepatocellular carcinoma (HCC):
HCC is the fifth most common malignancy in the world and complicates liver cirrhosis related to hepatitis C virus in many cases. Several studies have found that the antitumor activity of a novel ginseng saponin metabolite (IH-901) is attributable to the induction of apoptosis. The aim of the current study was to evaluate the therapeutic effects of KRG extract in Egyptian patients with chronic liver diseases.
Results:
This study results showed that the medical therapy alone failed to normalize the liver enzymes or decrease the virus concentration. Korean red ginseng administration induced a significant improvement in liver function tests, decreased the tumor marker levels, and decreased the viral titers in HCV patients.
Conclusion:
The results of the current study indicate that Korean red ginseng could act as liver cancer preventative as well as an antiviral agent against HCV.
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